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Evaluation of Hepatotoxicity with Off-Label Oral-Treatment Doses of Voriconazole for Invasive Fungal Infections
The approved treatment dose of intravenous voriconazole is a weight-based dose of 4 mg/kg of body weight twice daily; the approved oral dosing is fixed at 200 mg twice daily. In our institution, patients frequently receive oral high-dose voriconazole at 4 mg/kg twice daily. It is unknown if higher d...
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Auteurs principaux: | , , , , , |
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Format: | Artigo |
Langue: | Inglês |
Publié: |
American Society for Microbiology (ASM)
2011
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Sujets: | |
Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3019689/ https://ncbi.nlm.nih.gov/pubmed/20974867 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01078-10 |
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