Identification of the Tirandamycin Biosynthetic Gene Cluster From Streptomyces sp. 307-9

The structurally intriguing bicyclic ketal moiety of tirandamycin is common to several acyl-tetramic acid antibiotics, and is a key determinant of biological activity. We have identified the tirandamycin biosynthetic gene cluster from the environmental marine isolate Streptomyces sp. 307-9, thus pro...

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Bibliographic Details
Main Authors: Carlson, Jacob C., Fortman, J. L., Anzai, Yojiro, Li, Shengying, Burr, Douglas A., Sherman, David H.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3019614/
https://ncbi.nlm.nih.gov/pubmed/20127927
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cbic.200900658
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