Analysis of Three-dimensional Systems for Developing and Mature Kidneys Clarifies the Role of OAT1 and OAT3 in Antiviral Handling

The organic anion transporters OAT1 (SLC22A6, originally identified by us as NKT) and OAT3 (SLC22A8) are critical for handling many toxins, metabolites, and drugs, including antivirals (Truong, D. M., Kaler, G., Khandelwal, A., Swaan, P. W., and Nigam, S. K. (2008) J. Biol. Chem. 283, 8654–8663). Al...

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Autores principales: Nagle, Megha A., Truong, David M., Dnyanmote, Ankur V., Ahn, Sun-Young, Eraly, Satish A., Wu, Wei, Nigam, Sanjay K.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Membrane Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012981/
https://ncbi.nlm.nih.gov/pubmed/20921221
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.139949
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