The NOD2 Single Nucleotide Polymorphisms rs2066843 and rs2076756 Are Novel and Common Crohn's Disease Susceptibility Gene Variants

BACKGROUND: The aims were to analyze two novel NOD2 variants (rs2066843 and rs2076756) in a large cohort of patients with inflammatory bowel disease and to elucidate phenotypic consequences. METHODOLOGY/PRINCIPAL FINDINGS: Genomic DNA from 2700 Caucasians including 812 patients with Crohn's dis...

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Główni autorzy: Glas, Jürgen, Seiderer, Julia, Tillack, Cornelia, Pfennig, Simone, Beigel, Florian, Jürgens, Matthias, Olszak, Torsten, Laubender, Rüdiger P., Weidinger, Maria, Müller-Myhsok, Bertram, Göke, Burkhard, Ochsenkühn, Thomas, Lohse, Peter, Diegelmann, Julia, Czamara, Darina, Brand, Stephan
Format: Artigo
Język:Inglês
Wydane: Public Library of Science 2010
Hasła przedmiotowe:
Research Article
Dostęp online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012690/
https://ncbi.nlm.nih.gov/pubmed/21209938
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0014466
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