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BAC Modification through Serial or Simultaneous Use of CRE/Lox Technology

Bacterial Artificial Chromosomes (BACs) are vital tools in mouse genomic analyses because of their ability to propagate large inserts. The size of these constructs, however, prevents the use of conventional molecular biology techniques for modification and manipulation. Techniques such as recombinee...

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Bibliografiske detaljer
Main Authors: Parrish, Mark, Unruh, Jay, Krumlauf, Robb
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010708/
https://ncbi.nlm.nih.gov/pubmed/21197414
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2011/924068
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