Shikonin inhibits maturation of bone marrow-derived dendritic cells and suppresses allergic airway inflammation in a murine model of asthma

BACKGROUND AND PURPOSE: Shikonin exhibits a wide range of anti-inflammatory actions. Here, we assessed its effects on maturation of murine bone marrow-derived dendritic cells (BM-DCs) and on allergic reactions in a murine model of asthma. EXPERIMENTAL APPROACH: Cultured murine BM-DCs were used to in...

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Hlavní autoři: Lee, Chen-Chen, Wang, Chien-Neng, Lai, Yu-Ting, Kang, Jaw-Jou, Liao, Jiunn-Wang, Chiang, Bor-Luen, Chen, Hui-Chen, Cheng, Yu-Wen
Médium: Artigo
Jazyk:Inglês
Vydáno: Blackwell Science Inc 2010
Témata:
Research Papers
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010563/
https://ncbi.nlm.nih.gov/pubmed/20735407
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1476-5381.2010.00972.x
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