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Terameprocol (tetra-O-methyl nordihydroguaiaretic acid), an inhibitor of Sp1-mediated survivin transcription, induces radiosensitization in non-small cell lung carcinoma

INTRODUCTION: Survivin, an inhibitor of apoptosis protein (IAP) and key regulator of mitosis, is up-regulated in a variety of cancers and is often associated with a worse prognosis. Terameprocol down-regulates the Sp1-mediated transcription of survivin and Cdk1, which is important for cell cycle pro...

詳細記述

保存先:
書誌詳細
主要な著者: Sun, Yunguang, Giacalone, Nicholas J., Lu, Bo
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3010256/
https://ncbi.nlm.nih.gov/pubmed/21107289
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/JTO.0b013e3181fa646a
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