Somatic Mutation Profiles of MSI and MSS Colorectal Cancer Identified by Whole Exome Next Generation Sequencing and Bioinformatics Analysis

BACKGROUND: Colorectal cancer (CRC) is with approximately 1 million cases the third most common cancer worldwide. Extensive research is ongoing to decipher the underlying genetic patterns with the hope to improve early cancer diagnosis and treatment. In this direction, the recent progress in next ge...

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Main Authors: Timmermann, Bernd, Kerick, Martin, Roehr, Christina, Fischer, Axel, Isau, Melanie, Boerno, Stefan T., Wunderlich, Andrea, Barmeyer, Christian, Seemann, Petra, Koenig, Jana, Lappe, Michael, Kuss, Andreas W., Garshasbi, Masoud, Bertram, Lars, Trappe, Kathrin, Werber, Martin, Herrmann, Bernhard G., Zatloukal, Kurt, Lehrach, Hans, Schweiger, Michal R.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3008745/
https://ncbi.nlm.nih.gov/pubmed/21203531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015661
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