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Fitness Disadvantage of Transitional Intermediates Contributes to Dynamic Change in the Infecting-Virus Population during Coreceptor Switch in R5 Simian/Human Immunodeficiency Virus-Infected Macaques

Fitness disadvantage of the transitional intermediates compared to the initial R5 viruses has been suggested to constitute one of the blockades to coreceptor switching, explaining the late appearance of X4 viruses. Using a simian model for human immunodeficiency virus type 1 (HIV-1) coreceptor switc...

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Bibliografische gegevens
Hoofdauteurs: Shakirzyanova, Madina, Ren, Wuze, Zhuang, Ke, Tasca, Silvana, Cheng-Mayer, Cecilia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004298/
https://ncbi.nlm.nih.gov/pubmed/20943985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01478-10
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