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Fitness Disadvantage of Transitional Intermediates Contributes to Dynamic Change in the Infecting-Virus Population during Coreceptor Switch in R5 Simian/Human Immunodeficiency Virus-Infected Macaques

Fitness disadvantage of the transitional intermediates compared to the initial R5 viruses has been suggested to constitute one of the blockades to coreceptor switching, explaining the late appearance of X4 viruses. Using a simian model for human immunodeficiency virus type 1 (HIV-1) coreceptor switc...

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מידע ביבליוגרפי
Main Authors: Shakirzyanova, Madina, Ren, Wuze, Zhuang, Ke, Tasca, Silvana, Cheng-Mayer, Cecilia
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Microbiology (ASM) 2010
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3004298/
https://ncbi.nlm.nih.gov/pubmed/20943985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01478-10
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