A model for neural development and treatment of Rett Syndrome using human induced pluripotent stem cells

Autism spectrum disorders (ASD) are complex neurodevelopmental diseases in which different combinations of genetic mutations may contribute to the phenotype. Using Rett syndrome (RTT) as an ASD genetic model, we developed a culture system using induced pluripotent stem cells (iPSCs) from RTT patient...

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Hauptverfasser: Marchetto, Maria C. N., Carromeu, Cassiano, Acab, Allan, Yu, Diana, Yeo, Gene, Mu, Yangling, Chen, Gong, Gage, Fred H., Muotri, Alysson R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3003590/
https://ncbi.nlm.nih.gov/pubmed/21074045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2010.10.016
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