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Adiponectin may contribute to synovitis and joint destruction in rheumatoid arthritis by stimulating vascular endothelial growth factor, matrix metalloproteinase-1, and matrix metalloproteinase-13 expression in fibroblast-like synoviocytes more than proinflammatory mediators
INTRODUCTION: The role of adiponectin in the pathogenesis of arthritis is still controversial. This study was performed to examine whether adiponectin is involved in joint inflammation and destruction in rheumatoid arthritis (RA) in relation to the expression of vascular endothelial growth factor (V...
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Main Authors: | , , , , , , , , |
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Format: | Artigo |
Sprog: | Inglês |
Udgivet: |
BioMed Central
2009
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Fag: | |
Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3003518/ https://ncbi.nlm.nih.gov/pubmed/19883500 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar2844 |
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