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Cardiomyocyte NF-κB p65 promotes adverse remodelling, apoptosis, and endoplasmic reticulum stress in heart failure

AIMS: The role of nuclear factor (NF)-κB in heart failure (HF) is not well defined. We sought to determine whether myocyte-localized NF-κB p65 activation in HF exacerbates post-infarction remodelling and promotes maladaptive endoplasmic reticulum (ER) stress. METHODS AND RESULTS: Non-transgenic (NTg...

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Detalhes bibliográficos
Main Authors: Hamid, Tariq, Guo, Shang Z., Kingery, Justin R., Xiang, Xilin, Dawn, Buddhadeb, Prabhu, Sumanth D.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002872/
https://ncbi.nlm.nih.gov/pubmed/20797985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvq274
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