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A Scalable Approach for Discovering Conserved Active Subnetworks across Species

Overlaying differential changes in gene expression on protein interaction networks has proven to be a useful approach to interpreting the cell's dynamic response to a changing environment. Despite successes in finding active subnetworks in the context of a single species, the idea of overlaying...

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Bibliographic Details
Main Authors: Deshpande, Raamesh, Sharma, Shikha, Verfaillie, Catherine M., Hu, Wei-Shou, Myers, Chad L.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3000367/
https://ncbi.nlm.nih.gov/pubmed/21170309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1001028
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