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p53 status in stromal fibroblasts modulates tumor growth in an SDF1-dependent manner

The p53 tumor suppressor exerts a variety of cell-autonomous effects that are aimed to thwart tumor development. In addition, however, there is growing evidence for cell non-autonomous tumor suppressor effects of p53. In the present study, we investigated the impact of stromal p53 on tumor growth. S...

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Autores principales: Addadi, Yoseph, Moskovits, Neta, Granot, Dorit, Lozano, Guillermina, Carmi, Yaron, Apte, Ron N., Neeman, Michal, Oren, Moshe
Formato: Artigo
Lenguaje:Inglês
Publicado: 2010
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2999653/
https://ncbi.nlm.nih.gov/pubmed/20952507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-1146
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