All-or-None versus Graded: Single-Vesicle Analysis Reveals Lipid Composition Effects on Membrane Permeabilization

We report a single-vesicle approach to compare the all-or-none and graded mechanisms of lipid bilayer permeabilization by CpreTM and NpreTM, two peptides derived from the membrane-proximal external region of the HIV fusion glycoprotein gp41subunit. According to bulk requenching assays, these peptide...

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Bibliographic Details
Main Authors: Apellániz, Beatriz, Nieva, José L., Schwille, Petra, García-Sáez, Ana J.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2010
Subjects:
Membrane
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2998612/
https://ncbi.nlm.nih.gov/pubmed/21112286
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2010.09.027
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