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Population pharmacokinetic analysis of vancomycin in neonates. A new proposal of initial dosage guideline

AIM: To determine the population pharmacokinetic parameters of vancomycin in neonatal patients with a wide range of gestational age and birth weight, and subsequently to design an initial dosing schedule for vancomycin in neonates. METHODS: Using nonlinear mixed-effects modelling (NONMEM VI), the ph...

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Detalhes bibliográficos
Main Authors: Marqués-Miñana, María-Remedios, Saadeddin, Anas, Peris, José-Esteban
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2997311/
https://ncbi.nlm.nih.gov/pubmed/21039765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2010.03736.x
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