Increased inflammation and lethality of Dusp1(−/−) mice in polymicrobial peritonitis models

The mitogen-activated protein kinase phosphatase Dusp1 (also known as MKP-1) is essential for control of the inflammatory response to systemic challenge with the lipopolysaccharide of Gram-negative bacteria. Here, we have investigated the consequences of Dusp1-deficiency in colon ascendens stent per...

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Bibliographic Details
Main Authors: Hammer, Michael, Echtenachter, Bernd, Weighardt, Heike, Jozefowski, Katrin, Rose-John, Stefan, Männel, Daniela N, Holzmann, Bernhard, Lang, Roland
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2010
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Original Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2996560/
https://ncbi.nlm.nih.gov/pubmed/20561086
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2010.03313.x
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