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Hybridization properties of long nucleic acid probes for detection of variable target sequences, and development of a hybridization prediction algorithm
One of the main problems in nucleic acid-based techniques for detection of infectious agents, such as influenza viruses, is that of nucleic acid sequence variation. DNA probes, 70-nt long, some including the nucleotide analog deoxyribose-Inosine (dInosine), were analyzed for hybridization tolerance...
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| Main Authors: | , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2995084/ https://ncbi.nlm.nih.gov/pubmed/20864443 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq777 |
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