Inflammatory nociception diminishes dopamine release and increases dopamine D2 receptor mRNA in the rat's insular cortex

BACKGROUND: The insular cortex (IC) receives somatosensory afferent input and has been related to nociceptive input. It has dopaminergic terminals and D1 (D1R) -excitatory- and D2 (D2R) -inhibitory- receptors. D2R activation with a selective agonist, as well as D1R blockade with antagonists in the I...

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Autori principali: Coffeen, Ulises, Ortega-Legaspi, J Manuel, de Gortari, Patricia, Simón-Arceo, Karina, Jaimes, Orlando, Amaya, María Isabel, Pellicer, Francisco
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2994804/
https://ncbi.nlm.nih.gov/pubmed/21050459
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1744-8069-6-75
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