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DNA double-strand break signaling and human disorders

DNA double-strand breaks are among the most serious types of DNA damage and their signaling and repair is critical for all cells and organisms. The repair of both induced and programmed DNA breaks is fundamental as demonstrated by the many human syndromes, neurodegenerative diseases, immunodeficienc...

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Detalhes bibliográficos
Main Authors: Bohgaki, Toshiyuki, Bohgaki, Miyuki, Hakem, Razqallah
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993650/
https://ncbi.nlm.nih.gov/pubmed/21054854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2041-9414-1-15
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