Platelet CD40L mediates thrombotic and inflammatory processes in atherosclerosis

CD40 ligand (CD40L), identified as a costimulatory molecule expressed on T cells, is also expressed and functional on platelets. We investigated the thrombotic and inflammatory contributions of platelet CD40L in atherosclerosis. Although CD40L-deficient (Cd40l(−/−)) platelets exhibited impaired plat...

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Detaylı Bibliyografya
Asıl Yazarlar: Lievens, Dirk, Zernecke, Alma, Seijkens, Tom, Soehnlein, Oliver, Beckers, Linda, Munnix, Imke C. A., Wijnands, Erwin, Goossens, Pieter, van Kruchten, Roger, Thevissen, Larissa, Boon, Louis, Flavell, Richard A., Noelle, Randolph J., Gerdes, Norbert, Biessen, Erik A., Daemen, Mat J. A. P., Heemskerk, Johan W. M., Weber, Christian, Lutgens, Esther
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society of Hematology 2010
Konular:
Platelets and Thrombopoiesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993630/
https://ncbi.nlm.nih.gov/pubmed/20705757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2010-01-261206
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