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Abnormal Neurites Containing C-Terminally Truncated α-Synuclein Are Present in Alzheimer’s Disease without Conventional Lewy Body Pathology

The pathological hallmark of Parkinson’s disease and diffuse Lewy body disease (DLBD) is the aggregation of α-synuclein (α-syn) in the form of Lewy bodies and Lewy neurites. Patients with both Alzheimer’s disease (AD) and cortical Lewy pathology represent the Lewy body variant of AD (LBV) and consti...

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Détails bibliographiques
Auteurs principaux: Lewis, Karen A., Su, Yang, Jou, Olina, Ritchie, Caroline, Foong, Chan, Hynan, Linda S., White, Charles L., Thomas, Philip J., Hatanpaa, Kimmo J.
Format: Artigo
Langue:Inglês
Publié: American Society for Investigative Pathology 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993276/
https://ncbi.nlm.nih.gov/pubmed/21056999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2010.100552
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