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Apolipoprotein A-I Mimetic Peptides Prevent Atherosclerosis Development and Reduce Plaque Inflammation in a Murine Model of Diabetes

OBJECTIVE: To determine the effect of the apolipoprotein A-I (ApoA-I) mimetic peptide, D-4F, on atherosclerosis development in a pre-existing diabetic condition. RESEARCH DESIGN AND METHODS: We induced hyperglycemia in 6-week-old apoE(−/−) female mice using streptozotocin. Half of the diabetic apoE(...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Morgantini, Cecilia, Imaizumi, Satoshi, Grijalva, Victor, Navab, Mohamad, Fogelman, Alan M., Reddy, Srinivasa T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Diabetes Association 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992786/
https://ncbi.nlm.nih.gov/pubmed/20826564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0844
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