Prognostic and Predictive Gene Signature for Adjuvant Chemotherapy in Resected Non–Small-Cell Lung Cancer

PURPOSE: The JBR.10 trial demonstrated benefit from adjuvant cisplatin/vinorelbine (ACT) in early-stage non–small-cell lung cancer (NSCLC). We hypothesized that expression profiling may identify stage-independent subgroups who might benefit from ACT. PATIENTS AND METHODS: Gene expression profiling w...

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Autori principali: Zhu, Chang-Qi, Ding, Keyue, Strumpf, Dan, Weir, Barbara A., Meyerson, Matthew, Pennell, Nathan, Thomas, Roman K., Naoki, Katsuhiko, Ladd-Acosta, Christine, Liu, Ni, Pintilie, Melania, Der, Sandy, Seymour, Lesley, Jurisica, Igor, Shepherd, Frances A., Tsao, Ming-Sound
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society of Clinical Oncology 2010
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Original Reports
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2988634/
https://ncbi.nlm.nih.gov/pubmed/20823422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1200/JCO.2009.26.4325
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