An evaluation of the genetic-matched pair study design using genome-wide SNP data from the European population

Genetic matching potentially provides a means to alleviate the effects of incomplete Mendelian randomization in population-based gene–disease association studies. We therefore evaluated the genetic-matched pair study design on the basis of genome-wide SNP data (309 790 markers; Affymetrix GeneChip H...

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Main Authors: Lu, Timothy Tehua, Lao, Oscar, Nothnagel, Michael, Junge, Olaf, Freitag-Wolf, Sandra, Caliebe, Amke, Balascakova, Miroslava, Bertranpetit, Jaume, Bindoff, Laurence Albert, Comas, David, Holmlund, Gunilla, Kouvatsi, Anastasia, Macek, Milan, Mollet, Isabelle, Nielsen, Finn, Parson, Walther, Palo, Jukka, Ploski, Rafal, Sajantila, Antti, Tagliabracci, Adriano, Gether, Ulrik, Werge, Thomas, Rivadeneira, Fernando, Hofman, Albert, Uitterlinden, André Gerardus, Gieger, Christian, Wichmann, Heinz-Erich, Ruether, Andreas, Schreiber, Stefan, Becker, Christian, Nürnberg, Peter, Nelson, Matthew Roberts, Kayser, Manfred, Krawczak, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2986489/
https://ncbi.nlm.nih.gov/pubmed/19156175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ejhg.2008.266
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