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The HIV-1 Central Polypurine Tract Functions as a Second Line of Defense against APOBEC3G/F
HIV-1 and certain other retroviruses initiate plus-strand synthesis in the center of the genome as well as at the standard retroviral 3′ polypurine tract. This peculiarity of reverse transcription results in a central DNA “flap” structure that has been of controversial functional significance. We mu...
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| Main Authors: | , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Microbiology (ASM)
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2977901/ https://ncbi.nlm.nih.gov/pubmed/20844042 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00723-10 |
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