Influences of Sodium Carbonate on Physicochemical Properties of Lansoprazole in Designed Multiple Coating Pellets

Lansoprazole (LSP), a proton-pump inhibitor, belongs to class II drug. It is especially instable to heat, light, and acidic media, indicating that fabrication of a formulation stabilizing the drug is difficult. The addition of alkaline stabilizer is the most powerful method to protect the drug in so...

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Bibliographic Details
Main Authors: He, Wei, Yang, Min, Fan, Jun Hong, Feng, Cai Xia, Zhang, Su Juan, Wang, Jin Xu, Guan, Pei Pei, Wu, Wei
Format: Artigo
Language:Inglês
Published: Springer US 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974110/
https://ncbi.nlm.nih.gov/pubmed/20717759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9493-x
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