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Polyethylene Glycol on Stability of Chitosan Microparticulate Carrier for Protein

Stability enhancement of protein-loaded chitosan microparticles under storage was investigated. Chitosan glutamate at 35 kDa and bovine serum albumin as model protein drug were used in this study. The chitosan microparticles were prepared by ionotropic gelation, and polyethylene glycol 200 (PEG 200)...

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Bibliographic Details
Main Authors: Luangtana-anan, Manee, Limmatvapirat, Sontaya, Nunthanid, Jurairat, Chalongsuk, Rapeepun, Yamamoto, Keiji
Format: Artigo
Language:Inglês
Published: Springer US 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974106/
https://ncbi.nlm.nih.gov/pubmed/20821174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-010-9512-y
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