Manganese exposure inhibits the clearance of extracellular GABA and influences taurine homeostasis in the striatum of developing rats

Manganese (Mn) accumulation in the brain has been shown to alter the neurochemistry of the basal ganglia. Mn-induced alterations in dopamine biology are fairly well understood, but recently more evidence has emerged characterizing the role of γ-aminobutyric acid (GABA) in this dysfunction. The purpo...

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Hauptverfasser: Fordahl, Steve C., Anderson, Joel G., Cooney, Paula T., Weaver, Tara L., Colyer, Christa L., Erikson, Keith M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2974006/
https://ncbi.nlm.nih.gov/pubmed/20832424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuro.2010.09.002
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