Role of the gp85/Trans-Sialidases in Trypanosoma cruzi Tissue Tropism: Preferential Binding of a Conserved Peptide Motif to the Vasculature In Vivo

BACKGROUND: Transmitted by blood-sucking insects, the unicellular parasite Trypanosoma cruzi is the causative agent of Chagas' disease, a malady manifested in a variety of symptoms from heart disease to digestive and urinary tract dysfunctions. The reasons for such organ preference have been a...

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Bibliographic Details
Main Authors: Tonelli, Renata R., Giordano, Ricardo J., Barbu, Elena Magda, Torrecilhas, Ana Claudia, Kobayashi, Gerson S., Langley, Robert R., Arap, Wadih, Pasqualini, Renata, Colli, Walter, Alves, Maria Júlia M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2010
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2970537/
https://ncbi.nlm.nih.gov/pubmed/21072227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000864
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