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Apoptosis induced by ozone and oxysterols in human alveolar epithelial cells

The mechanism of ozone-induced lung cell injury is poorly understood. One hypothesis is that ozone induces lipid peroxidation and that these peroxidased lipids produce oxidative stress and DNA damage. Oxysterols are lipid peroxide formed by the direct effect of ozone on pulmonary surfactant and cell...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kosmider, Beata, Loader, Joan E., Murphy, Robert C., Mason, Robert J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965594/
https://ncbi.nlm.nih.gov/pubmed/20219673
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2010.02.032
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