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MultiRTA: A simple yet reliable method for predicting peptide binding affinities for multiple class II MHC allotypes

BACKGROUND: The binding of peptide fragments of antigens to class II MHC is a crucial step in initiating a helper T cell immune response. The identification of such peptide epitopes has potential applications in vaccine design and in better understanding autoimmune diseases and allergies. However, c...

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Detalhes bibliográficos
Main Authors: Bordner, Andrew J, Mittelmann, Hans D
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957400/
https://ncbi.nlm.nih.gov/pubmed/20868497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-482
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