Two insulin-like peptide family members from the mosquito Aedes aegypti exhibit differential biological and receptor binding activities

Insects encode multiple ILPs but only one homolog of the vertebrate IR that activates the insulin signaling pathway. However, it remains unclear whether all insect ILPs are high affinity ligands for the IR or have similar biological functions. The yellow fever mosquito, Aedes aegypti, encodes eight...

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Bibliographic Details
Main Authors: Wen, Zhimou, Gulia, Monika, Clark, Kevin D., Dhara, Animesh, Crim, Joe W., Strand, Michael R., Brown, Mark R.
Format: Artigo
Language:Inglês
Published: 2010
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2957182/
https://ncbi.nlm.nih.gov/pubmed/20643184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2010.07.003
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