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P-Glycoprotein/MDR1 Regulates Pokemon Gene Transcription Through p53 Expression in Human Breast Cancer Cells

P-glycoprotein (Pgp), encoded by the multidrug resistance 1 (MDR1) gene, is an efflux transporter and plays an important role in pharmacokinetics. In this study, we demonstrated that the pokemon promoter activity, the pokemon mRNA and protein expression can be significantly inhibited by Pgp. Chromat...

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Bibliografski detalji
Glavni autori: He, Shengnan, Liu, Feng, Xie, Zhenhua, Zu, Xuyu, Xu, Wei, Jiang, Yuyang
Format: Artigo
Jezik:Inglês
Izdano: Molecular Diversity Preservation International (MDPI) 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956079/
https://ncbi.nlm.nih.gov/pubmed/20957096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms11093039
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