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P-Glycoprotein/MDR1 Regulates Pokemon Gene Transcription Through p53 Expression in Human Breast Cancer Cells

P-glycoprotein (Pgp), encoded by the multidrug resistance 1 (MDR1) gene, is an efflux transporter and plays an important role in pharmacokinetics. In this study, we demonstrated that the pokemon promoter activity, the pokemon mRNA and protein expression can be significantly inhibited by Pgp. Chromat...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: He, Shengnan, Liu, Feng, Xie, Zhenhua, Zu, Xuyu, Xu, Wei, Jiang, Yuyang
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Molecular Diversity Preservation International (MDPI) 2010
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956079/
https://ncbi.nlm.nih.gov/pubmed/20957096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms11093039
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