Parsing the Effects of Individual SNPs in Candidate Genes with Family Data

We introduce a stepwise approach for family-based designs for selecting a set of markers in a gene that are independently associated with the disease. The approach is based on testing the effect of a set of markers conditional on another set of markers. Several likelihood-based approaches have been...

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Главные авторы: Hoffmann, Thomas J., Lange, Christoph, Vansteelandt, Stijn, Raby, Benjamin A., DeMeo, Dawn L., Silverman, Edwin K., Weiss, Scott T., Laird, Nan M.
Формат: Artigo
Язык:Inglês
Опубликовано: S. Karger AG 2010
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Original Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2956011/
https://ncbi.nlm.nih.gov/pubmed/19996607
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000264447
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