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IKKα Contributes to Canonical NF-κB Activation Downstream of Nod1-Mediated Peptidoglycan Recognition

BACKGROUND: During pathogen infection, innate immunity is initiated via the recognition of microbial products by pattern recognition receptors and the subsequent activation of transcription factors that upregulate proinflammatory genes. By controlling the expression of cytokines, chemokines, anti-ba...

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Main Authors: Kim, Man Lyang, Jeong, Hyun Gyeong, Kasper, Christoph Alexander, Arrieumerlou, Cécile
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955547/
https://ncbi.nlm.nih.gov/pubmed/20976174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015371
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