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In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene.

Elevations of plasma total or LDL cholesterol are major risk factors for cardiovascular disease. Efforts directed at preventing and treating cardiovascular disease have often focused on reducing the levels of these substances in the blood. The Watanabe Heritable Hyperlipidemic Rabbit, which has exce...

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Main Authors: Li, J, Fang, B, Eisensmith, R C, Li, X H, Nasonkin, I, Lin-Lee, Y C, Mims, M P, Hughes, A, Montgomery, C D, Roberts, J D
Formato: Artigo
Idioma:Inglês
Publicado: 1995
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC295550/
https://ncbi.nlm.nih.gov/pubmed/7860759
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