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In vivo gene therapy for hyperlipidemia: phenotypic correction in Watanabe rabbits by hepatic delivery of the rabbit LDL receptor gene.

Elevations of plasma total or LDL cholesterol are major risk factors for cardiovascular disease. Efforts directed at preventing and treating cardiovascular disease have often focused on reducing the levels of these substances in the blood. The Watanabe Heritable Hyperlipidemic Rabbit, which has exce...

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Hlavní autoři: Li, J, Fang, B, Eisensmith, R C, Li, X H, Nasonkin, I, Lin-Lee, Y C, Mims, M P, Hughes, A, Montgomery, C D, Roberts, J D
Médium: Artigo
Jazyk:Inglês
Vydáno: 1995
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC295550/
https://ncbi.nlm.nih.gov/pubmed/7860759
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