Measuring the rate of progression in Friedreich ataxia: Implications for clinical trial design

Friedreich ataxia is an autosomal recessive neurodegenerative disorder characterized by ataxia of all four limbs, dysarthria and arreflexia. A variety of measures are currently used to quantify disease progression, including the Friedreich Ataxia Rating Scale, examiner-rated functional disability sc...

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Autori principali: Friedman, Lisa S, Farmer, Jennifer M, Perlman, Susan, Wilmot, George, Gomez, Christopher, Bushara, Khalaf O, Mathews, Katherine D, Subramony, S. H, Ashizawa, Tetsuo, Balcer, Laura J, Wilson, Robert B, Lynch, David R
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2954653/
https://ncbi.nlm.nih.gov/pubmed/20063431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mds.22912
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