CD8(+) T Cells as a Source of IFN-γ Production in Human Cutaneous Leishmaniasis

BACKGROUND: In human leishmaniasis Th1/Th2 dichotomy similar to murine model is not clearly defined and surrogate marker(s) of protection is not yet known. In this study, Th1/Th2 cytokines (IL-5, IL-10, IL-13 and IFN-γ) profile induced by purified CD4(+)/CD8(+) T cells in response to Leishmania anti...

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Main Authors: Nateghi Rostami, Mahmoud, Keshavarz, Hossein, Edalat, Rosita, Sarrafnejad, Abdolfattah, Shahrestani, Tahereh, Mahboudi, Fereidoun, Khamesipour, Ali
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2010
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2953482/
https://ncbi.nlm.nih.gov/pubmed/20967288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0000845
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