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Increased seizure severity and seizure-related death in mice lacking HCN1 channels

Persistent down-regulation in the expression of the hyperpolarization-activated HCN1 cation channel, a key determinant of intrinsic neuronal excitability, has been observed in febrile seizure, temporal lobe epilepsy and generalized epilepsy animal models, as well as patients with epilepsy. However,...

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Detaylı Bibliyografya
Asıl Yazarlar: Santoro, Bina, Lee, Janet Y., Englot, Dario J., Gildersleeve, Sandra, Piskorowski, Rebecca A., Siegelbaum, Steven A., Winawer, Melodie R., Blumenfeld, Hal
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2010
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2952649/
https://ncbi.nlm.nih.gov/pubmed/20384728
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2010.02554.x
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