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Increased seizure severity and seizure-related death in mice lacking HCN1 channels
Persistent down-regulation in the expression of the hyperpolarization-activated HCN1 cation channel, a key determinant of intrinsic neuronal excitability, has been observed in febrile seizure, temporal lobe epilepsy and generalized epilepsy animal models, as well as patients with epilepsy. However,...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2952649/ https://ncbi.nlm.nih.gov/pubmed/20384728 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1528-1167.2010.02554.x |
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