Preparation and in vitro characterization of 9-nitrocamptothecin-loaded long circulating nanoparticles for delivery in cancer patients

The purpose in this study was to investigate poly(ethylene glycol)-modified poly (d,l-lactide-co-glycolide) nanoparticles (PLGA-PEG-NPs) loading 9-nitrocamptothecin (9-NC) as a potent anticancer drug. 9-NC is an analog of the natural plant alkaloid camptothecin that has shown high antitumor activity...

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Bibliographic Details
Main Authors: Derakhshandeh, Katayoun, Soheili, Marzieh, Dadashzadeh, Simin, Saghiri, Reza
Format: Artigo
Language:Inglês
Published: Dove Medical Press 2010
Subjects:
Original Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2950404/
https://ncbi.nlm.nih.gov/pubmed/20957168
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