Mutations Disrupting Selenocysteine Formation Cause Progressive Cerebello-Cerebral Atrophy

The essential micronutrient selenium is found in proteins as selenocysteine (Sec), the only genetically encoded amino acid whose biosynthesis occurs on its cognate tRNA in humans. In the final step of selenocysteine formation, the essential enzyme SepSecS catalyzes the conversion of Sep-tRNA to Sec-...

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Main Authors: Agamy, Orly, Ben Zeev, Bruria, Lev, Dorit, Marcus, Barak, Fine, Dina, Su, Dan, Narkis, Ginat, Ofir, Rivka, Hoffmann, Chen, Leshinsky-Silver, Esther, Flusser, Hagit, Sivan, Sara, Söll, Dieter, Lerman-Sagie, Tally, Birk, Ohad S.
格式: Artigo
語言:Inglês
出版: Elsevier 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2948803/
https://ncbi.nlm.nih.gov/pubmed/20920667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2010.09.007
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