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FVB mouse genotype confers susceptibility to OVE26 diabetic albuminuria

OVE26 (OVE) diabetic mice on the inbred strain FVB are a valuable model of diabetic nephropathy that excretes the highest amount of urine albumin of all diabetic mouse models. Crossing of OVE mice to C57BL6 or DBA2 mice reduced albuminuria 17-fold in F1 diabetic offspring without reducing diabetes....

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Main Authors: Xu, Jianxiang, Huang, Yun, Li, Fenge, Zheng, Shirong, Epstein, Paul N.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944296/
https://ncbi.nlm.nih.gov/pubmed/20610531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00018.2010
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