Microenvironment alters epigenetic and gene expression profiles in Swarm rat chondrosarcoma tumors

BACKGROUND: Chondrosarcomas are malignant cartilage tumors that do not respond to traditional chemotherapy or radiation. The 5-year survival rate of histologic grade III chondrosarcoma is less than 30%. An animal model of chondrosarcoma has been established - namely, the Swarm Rat Chondrosarcoma (SR...

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Main Authors: Hamm, Christopher A, Stevens, Jeff W, Xie, Hehuang, Vanin, Elio F, Morcuende, Jose A, Abdulkawy, Hakeem, Seftor, Elisabeth A, Sredni, Simone T, Bischof, Jared M, Wang, Deli, Malchenko, Sergey, de Fatima Bonaldo, Maria, Casavant, Thomas L, Hendrix, Mary JC, Soares, Marcelo B
Format: Artigo
Language:Inglês
Published: BioMed Central 2010
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944175/
https://ncbi.nlm.nih.gov/pubmed/20809981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-10-471
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