Cdc42 interacting protein 4 (CIP4) is essential for integrin-dependent T-cell trafficking

The F-BAR domain containing protein CIP4 (Cdc42 interacting protein 4) interacts with Cdc42 and WASP/N-WASP and is thought to participate in the assembly of filamentous actin. CIP4(−/−) mice had normal T- and B-lymphocyte development but impaired T cell-dependent antibody production, IgG antibody af...

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Autori principali: Koduru, Suresh, Kumar, Lalit, Massaad, Michel J., Ramesh, Narayanaswamy, Le Bras, Séverine, Ozcan, Esra, Oyoshi, Michiko K., Kaku, Mayumi, Fujiwara, Yuko, Kremer, Leonor, King, Sandra, Fuhlbrigge, Robert, Rodig, Scott, Sage, Peter, Carman, Chris, Alcaide, Pilar, Luscinskas, Francis W., Geha, Raif S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2010
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941295/
https://ncbi.nlm.nih.gov/pubmed/20805498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1002747107
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