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Osteoclast Inhibitory Peptide-1 Binding to the FcγRIIB Inhibits Osteoclast Differentiation

Osteoclast inhibitory peptide-1 (OIP) is an autocrine/paracrine inhibitor of osteoclast differentiation, and mice that overexpress OIP-1 in osteoclast lineage cells develop an osteopetrosis bone phenotype. In this study, we show that OIP-1 binding to the Fcγ receptor IIB (FcγRIIB) inhibits osteoclas...

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Détails bibliographiques
Auteurs principaux: Shanmugarajan, Srinivasan, Beeson, Craig C., Reddy, Sakamuri V.
Format: Artigo
Langue:Inglês
Publié: The Endocrine Society 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2940506/
https://ncbi.nlm.nih.gov/pubmed/20610564
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2010-0244
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